Abstract
The precautionary principle is often put forward as potentially useful guide to avoiding catastrophe under conditions of uncertainty. But finding an adequate formulation of the principle runs into a problem when needed precautionary measures also have potentially catastrophic consequences – the imperative to avoid catastrophe appears to recommend both for and against the measures. Drawing from the early pandemic, we suggest a way around this “problem of paralysis”: We should recognize and incorporate an asymmetry between our options, based on whether there is a possibility of intervening later to prevent the worst outcome.